primobolan depot cycle

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Indications for use . Primobolan depot cycle men and women, due to a violation of activity of the hypothalamus and pituitary gland.

In women: anovulatory infertility, failure of the corpus luteum (the presence of estrogenic ovarian function), the induction of superovulation during assisted reproductive techniques, habitual miscarriage, threatening spontaneous miscarriage.
Men : gipogenitalizme, syndrome; testicular hypoplasia, cryptorchidism; adiposogenital syndrome, pituitary dwarfism, sexual infantilism; oligoastenospermiya, azoospermia.
In order differential diagnosis of cryptorchidism and anarchism in boys and to assess testicular function with hypogonadotropic hypogonadism.

Contraindications . Hypersensitivity to the drug, pituitary tumors, hormone-active tumors of the reproductive glands (including androgen), the absence of sex glands (congenital or after surgery), early menopause, thrombophlebitis, lactation, ovarian cancer, hypothyroidism, adrenal insufficiency , hyperprolactinemia, obstruction of the fallopian tubes.

Precautions : adolescence, coronary heart disease, hypertension, chronic renal failure, asthma, migraine.

Dosage and administration . The drug is administered intramuscularly.
Women for ovulation induction – simultaneously 5000-10000 units, stimulation of the corpus luteum function – 1500-5000 IU 3-6-9 days after ovulation.
To induce superovulation in the course of assisted reproduction activities – up to 10,000 IU once after induction of multiple follicular growth, which is achieved as a result of stimulation by the established pattern. Fence egg produced through 34-36 hours after administration.
When habitual miscarriage administration begin as soon as the pregnancy is diagnosed (but not later than 8 weeks), and continued until 14 weeks of primobolan depot cycle pregnancy, inclusive: Day 1 – 10,000 units, followed by 5,000 IU 2 times a week.
When threatened spontaneous abortion (if symptoms have appeared in the first eight weeks of gestation) – 10000 U initially, followed by 5000 units two times a week until 14 weeks of gestation, inclusive.
if the delay puberty boys – at 3000-5000 ME 1 once a week for at least 3 months. For men – 500-2000 IU 1 time per day 2-3 times per week for 1.5-3 months.
In hypogonadotropic hypogonadism: 1500-6000 IU (in combination with menotropinami) 1 times a week.
For the purpose of differential diagnosis of cryptorchidism and anarchism boys and to assess testicular function with hypogonadotropic hypogonadism, odnokratno- 5000 IU.
if cryptorchidism: the age of 6 years – 500-1000 IU 2 times a week for 6 weeks; over 6 years – 1500 IU 2 times a week for 6 weeks.
When normogonadotropic idiopathic oligospermia – 5000 IU weekly for 3 months with menotropinami. When oligosaccharides and astenospermii due to relative androgen deficiency – 2500 IU every 5 days, or 10,000 IU 1 every 2 weeks for 3 months.

Side effect . Local reactions (injection site pain, flushing); allergic reactions; headache; fatigue; irritability; anxiety; depression; suppressing gonadotropic pituitary function.
In women with infertility combined treatment (in combination with clomiphene and menotropinami) – ovarian hyperstimulation syndrome. The men – fluid retention, edema, hypersensitivity nipple breast, gynecomastia, increased testicle in the inguinal canal (with cryptorchidism).
As a result, long-term use of the drug in men found a decrease in the number of sperm in the ejaculate.

Overdose . If overdose can occur in women of ovarian hyperstimulation syndrome with increasing their size by ovarian cysts with danger of rupture, the occurrence of ascites and hydrothorax. Its appearance may indicate symptoms such as a feeling of tension and pain in the abdomen, vomiting, diarrhea, shortness of breath, weight gain. Treatment – symptomatic.

Interaction with other medicinal products . Chorionic primobolan depot cycle gonadotropin is used in conjunction with the treatment of menopausal gonadotropin infertility.

Specific guidance .
In men, the drug is not effective at high levels of follicle stimulating hormone (FSH). In long-term treatment or use at high doses in male adolescents with impaired physical and sexual development may precocious puberty. Unreasonably long application of the drug in cryptorchidism, especially if indicated surgery may lead to the degeneration of the gonads. Inhibition of production of FSH due to stimulation of the production of androgens and estrogens contribute to atrophy of the seminiferous tubules.
Chronic exposure can lead to the formation of antibodies to the drug.
It increases the risk of multiple pregnancy. Possible erroneous results when using a pregnancy test at the time of treatment and within 7 days after its cancellation.

Product form . Valium for drug of a solution for intramuscular injection of 5000 IU in 5 ml vials.
At 5 bottles with the drug in blisters and 5 vials of 1 ml of sodium chloride solution for injection to 0.9% in blisters together with instructions for use of the drug and solvent is placed in a cardboard box.

Storage conditions . List B. In the dark and inaccessible to children at temperature not above 20 ° C.

Shelf life . 3 years.
Do not use beyond the expiration date printed on the package. steroiden kaufen

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